SCHEMBL2010270 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	6/20	0.50

▸	KMT2A	Q03164	6/20	0.50

▸	RAB9A	P51151	1/20	0.50

▸	HPGD	P15428	1/20	0.47

▸	GAA	P10253	2/20	0.46

▸	FKBP1A	P62942	4/20	0.43

▸	MEN1	O00255	5/20	0.42

▸	LMNA	P02545	1/20	0.41

▸	SMN1; SMN2	Q16637	1/20	0.41

▸	MAPK1	P28482	1/20	0.40

▸	NPSR1	Q6W5P4	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12628483	1.00	ALDH1A1 (0.50)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL2011503	0.94	ALDH1A1 (0.48)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL12628509	0.94	ALDH1A1 (0.48)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL2010855	0.88	ALDH1A1 (0.53)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL12628511	0.88	ALDH1A1 (0.53)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL2012239	0.87	GAA (0.51)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL12628173	0.87	GAA (0.51)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL2013179	0.86	HPGD (0.65)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL12628176	0.86	HPGD (0.65)	ALDH1A1KMT2ARAB9AHPGDGAA
SCHEMBL2017075	0.84	HPGD (0.52)	ALDH1A1KMT2ARAB9AHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011073269-A1	PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS	EVOTEC AG (DE)	2011-06-23	—	—	WO	claimed