Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628511 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL2012055 | 0.91 | LMNA (0.48) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL12632352 | 0.91 | LMNA (0.48) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL12628483 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL12628173 | 0.88 | GAA (0.51) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL2012239 | 0.88 | GAA (0.51) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL2010270 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL2013179 | 0.87 | HPGD (0.65) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL12628176 | 0.87 | HPGD (0.65) | ALDH1A1KMT2ARAB9AGAAHPGD | |
| SCHEMBL12628159 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KMT2ARAB9AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |