Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628509 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KMT2ARAB9AFKBP1AHPGD | |
| SCHEMBL2010270 | 0.94 | ALDH1A1 (0.50) | ALDH1A1KMT2ARAB9AFKBP1AHPGD | |
| SCHEMBL12628483 | 0.94 | ALDH1A1 (0.50) | ALDH1A1KMT2ARAB9AFKBP1AHPGD | |
| SCHEMBL12628173 | 0.89 | GAA (0.51) | ALDH1A1KMT2ARAB9AFKBP1AHPGD | |
| SCHEMBL2012239 | 0.89 | GAA (0.51) | ALDH1A1KMT2ARAB9AFKBP1AHPGD | |
| SCHEMBL12628511 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9AFKBP1AHPGD | |
| SCHEMBL2010855 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9AFKBP1AHPGD | |
| SCHEMBL12629077 | 0.85 | FKBP1A (0.60) | ALDH1A1KMT2ARAB9AFKBP1AGAA | |
| SCHEMBL2012296 | 0.85 | FKBP1A (0.60) | ALDH1A1KMT2ARAB9AFKBP1AGAA | |
| SCHEMBL12628176 | 0.84 | HPGD (0.65) | ALDH1A1KMT2ARAB9AFKBP1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |