Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652880 | 0.83 | ANPEP (0.37) | ANPEPDNPEPCYP2D6CYP2C19KMT2A | |
| SCHEMBL12268658 | 0.80 | GAA (0.40) | ANPEPDNPEPKMT2AMEN1DPP4 | |
| SCHEMBL10311696 | 0.80 | CYP2D6 (0.39) | ANPEPDNPEPCYP2D6CYP2C19KMT2A | |
| SCHEMBL17680117 | 0.80 | CYP2D6 (0.39) | ANPEPDNPEPCYP2D6CYP2C19KMT2A | |
| SCHEMBL10311725 | 0.80 | CYP2D6 (0.39) | ANPEPDNPEPCYP2D6CYP2C19KMT2A | |
| SCHEMBL10072998 | 0.80 | CYP2D6 (0.39) | ANPEPDNPEPCYP2D6CYP2C19KMT2A | |
| SCHEMBL13534167 | 0.80 | CYP2D6 (0.39) | ANPEPDNPEPCYP2D6CYP2C19KMT2A | |
| SCHEMBL27678507 | 0.79 | ALDH1A1 (0.39) | ANPEPDNPEPCYP2D6CYP2C19KMT2A | |
| SCHEMBL1769047 | 0.77 | GFPT1 (0.49) | — | |
| SCHEMBL21973387 | 0.77 | ANPEP (0.34) | ANPEPDNPEPCYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118790-A1 | Synthetic Beta-Amyloid Peptides Capable of Forming Stable Antigenic Oligomers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-03 | — | — | US | disclosed |