SCHEMBL10072998

SCHEMBL10072998

CC(O)CNC(=O)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 2/20 0.37
CYP2C9 P11712 1/20 0.37
ERCC1 P07992 1/20 0.37
ERCC4 Q92889 1/20 0.37
MEN1 O00255 1/20 0.35
ANPEP P15144 1/20 0.34
DNPEP Q9ULA0 1/20 0.34
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
PTGS2 P35354 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ACR P10323 1/20 0.33
MMP1 P03956 1/20 0.33
MMP8 P22894 1/20 0.33
NEU3 Q9UQ49 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10311696 1.00 CYP2D6 (0.39) CYP2D6CYP2C19ALDH1A1KMT2ACYP2C9
SCHEMBL10311725 1.00 CYP2D6 (0.39) CYP2D6CYP2C19ALDH1A1KMT2ACYP2C9
SCHEMBL17680117 0.84 CYP2D6 (0.39) CYP2D6CYP2C19ALDH1A1KMT2ACYP2C9
SCHEMBL13534167 0.84 CYP2D6 (0.39) CYP2D6CYP2C19ALDH1A1KMT2ACYP2C9
SCHEMBL1582718 0.84 MEN1 (0.50) CYP2D6CYP2C19ALDH1A1KMT2AMEN1
SCHEMBL21185864 0.84 CYP2D6 (0.39) CYP2D6CYP2C19ALDH1A1KMT2AMEN1
SCHEMBL3354440 0.81 CYP2D6 (0.59) CYP2D6CYP2C19ALDH1A1KMT2ACYP2C9
SCHEMBL20102958 0.80 ANPEP (0.40) CYP2D6CYP2C19ALDH1A1KMT2ACYP2C9
SCHEMBL7223053 0.80 ANPEP (0.40) CYP2D6CYP2C19ALDH1A1KMT2AMEN1
SCHEMBL1808926 0.80 ANPEP (0.40) CYP2D6CYP2C19ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534834-A Polymer, preparation method and application thereof, and intrinsic low-temperature curing negative photoresist 上海交通大学 2024-02-09 CN claimed
WO-2024094645-A1 NONSTICK POLYMER COATINGS FOR SHORT-TERM IMPLANTS Universität Siegen (DE) 2024-05-10 WO disclosed
CN-117534834-A Polymer, preparation method and application thereof, and intrinsic low-temperature curing negative photoresist 上海交通大学 2024-02-09 CN disclosed
WO-2023210671-A1 COPOLYMER, POLYMER FILM, MEASURING DEVICE, AND SUPPORT FOR MEASUREMENT 京セラ株式会社 2023-11-02 WO disclosed
US-11633486-B2 Polymer materials for delivery of short-chain fatty acids to the intestine for applications in human health and treatment of disease THE UNIVERSITY OF CHICAGO (US) 2023-04-25 US disclosed
US-20220388964-A1 (AZA)INDAZOLYL-ARYL SULFONAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS HIBERCELL, INC. 2022-12-08 US disclosed
US-20210300940-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2021-09-30 US disclosed
US-11053216-B2 Compounds and methods of use MEDIVATION TECHNOLOGIES LLC (US) 2021-07-06 US disclosed
US-20210069120-A1 COMPOSITE NANOPARTICLE, PREPARATION METHOD THEREOF AND PREPARATION METHOD OF COMPOSITE NANO PREPARATION USING THEREOF JINAN UNIVERSITY (CN) 2021-03-11 US disclosed
US-20210000934-A1 POLYMER ADJUVANT OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2021-01-07 US disclosed
US-20110118362-A1 POLYMERS FOR CARDIOPULMONARY THERAPIES UNIVERSITY OF UTAH RESEARCH FOUNDATION 2011-05-19 US disclosed
US-20110085979-A1 CONJUGATE OF A POLYMER, AN ANTI-ANGIOGENESIS AGENT AND A TARGETING MOIETY, AND USES THEREOF IN THE TREATMENT OF BONE RELATED ANGIOGENESIS CONDITIONS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2011-04-14 US disclosed
US-20110086111-A1 POLYMERIC SYSTEMS FOR THE DELIVERY OF ANTICANCER DRUGS REXAHN PHARMACEUTICALS, INC. (US) 2011-04-14 US disclosed
US-7919076-B2 PH-sensitive polymeric conjugates of an anthracycline cancerostatic drug for targeted therapy ZENTIVA, K.S. (CZ) 2011-04-05 US disclosed
WO-2010141330-A1 DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-12-09 WO disclosed
WO-2010045896-A2 POLYMERIC COMPOSITION WITH SYNERGISTIC EFFECT IN TREATMENT OF TUMOUR DISEASES ZENTIVA, K.S. (CZ) 2010-04-29 WO disclosed
US-7691879-B2 Isoquinoline potassium channel inhibitors MERCK SHARP & DOHME CORP. (US) 2010-04-06 US disclosed
US-20090311182-A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-12-17 US disclosed
EP-1782833-A2 pH-sensitive polymeric conjugates of an anthracycline cancerostatic drug for targeted therapy ZENTIVA, A.S. (CZ) 2007-05-09 EP disclosed
US-20070049603-A1 Raf inhibitor compounds and methods of use thereof ARRAY BIOPHARMA INC. 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210000934-A1 POLYMER ADJUVANT TLR3, TLR9, TLR1 CYP2D6 4837/4885CYP2C19 4855/4885ALDH1A1 3788/4885
US-20110086111-A1 POLYMERIC SYSTEMS FOR THE DELIVERY OF ANTICANCER DRUGS APEH, LNPEP, CPA3 CYP2D6 2677/4885CYP2C19 2206/4885ALDH1A1 989/4885
US-20110085979-A1 CONJUGATE OF A POLYMER, AN ANTI-ANGIOGENESIS AGENT AND A TARGETING MOIETY, AND USES THEREOF IN THE TREATMENT OF BONE RELATED ANGIOGENESIS CONDITIONS VEGFA, MVD, FLT1 CYP2D6 4533/4885CYP2C19 4545/4885ALDH1A1 2529/4885
US-20070049603-A1 Raf inhibitor compounds and methods of use thereof BRAF, RAF1, ARAF CYP2D6 3584/4885CYP2C19 4116/4885ALDH1A1 1842/4885
US-11633486-B2 Polymer materials for delivery of short-chain fatty acids to the intestine for applications in human health and treatment of disease SI, FABP2, VIP CYP2D6 2243/4885CYP2C19 1437/4885ALDH1A1 1366/4885
US-20110118362-A1 POLYMERS FOR CARDIOPULMONARY THERAPIES TNNI3, TNNT2, TNNC1 CYP2D6 3612/4885CYP2C19 2584/4885ALDH1A1 1799/4885
US-11053216-B2 Compounds and methods of use TGFB2, TGFB1, HDGF CYP2D6 4782/4885CYP2C19 4882/4885ALDH1A1 1992/4885
US-20090311182-A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases MMP1, MSR1, CD68 CYP2D6 4618/4885CYP2C19 4862/4885ALDH1A1 4050/4885
US-20210300940-A1 TLR7/8 ANTAGONISTS AND USES THEREOF TLR7, TLR8, TLR9 CYP2D6 2475/4885CYP2C19 2784/4885ALDH1A1 2764/4885
US-20220388964-A1 (AZA)INDAZOLYL-ARYL SULFONAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS EIF2AK4, GCN1, GNAI2 CYP2D6 908/4885CYP2C19 506/4885ALDH1A1 1814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.