Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21688306 | 1.00 | FFAR1 (0.41) | FFAR1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL21688298 | 0.82 | FFAR1 (0.43) | FFAR1MAPK1KMT2ANPC1RAB9A | |
| SCHEMBL20103527 | 0.79 | FFAR1 (0.44) | FFAR1RAB9A | |
| SCHEMBL20103443 | 0.79 | FFAR1 (0.44) | FFAR1RAB9A | |
| SCHEMBL20103446 | 0.79 | FFAR1 (0.44) | FFAR1RAB9A | |
| SCHEMBL21688395 | 0.78 | FFAR1 (0.43) | FFAR1ALDH1A1PTGS1 | |
| SCHEMBL20103672 | 0.78 | FFAR1 (0.57) | FFAR1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL21688303 | 0.76 | FFAR1 (0.46) | FFAR1MEN1KMT2A | |
| SCHEMBL20103532 | 0.76 | FFAR1 (0.46) | FFAR1MEN1KMT2A | |
| SCHEMBL21644971 | 0.75 | ITGB3 (0.40) | FFAR1MAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |