Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15371487 | 0.74 | GABRA1 (0.44) | ALDH1A1GABRA1GABRB2SLC6A2SLC6A4 | |
| SCHEMBL28264058 | 0.72 | TAS1R3 (0.31) | MEN1KMT2AHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL28264059 | 0.72 | TAS1R3 (0.31) | MEN1KMT2AHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL28264060 | 0.72 | TAS1R3 (0.31) | MEN1KMT2AHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL8750412 | 0.72 | L3MBTL1 (0.42) | TP53GABRA1GABRB2SLC6A2SLC6A4 | |
| SCHEMBL13955720 | 0.68 | SMN1; SMN2 (0.40) | ALDH1A1MEN1KMT2AHSD17B10GABRA1 | |
| SCHEMBL18242187 | 0.66 | TAS1R3 (0.40) | ALDH1A1MEN1KMT2AHSD17B10GABRA1 | |
| SCHEMBL12770134 | 0.66 | CYP1A2 (0.59) | ALDH1A1TP53MEN1KMT2AHSD17B10 | |
| SCHEMBL13490568 | 0.66 | L3MBTL1 (0.47) | ALDH1A1TP53MEN1KMT2AGABRA1 | |
| SCHEMBL14349302 | 0.65 | TAS1R3 (0.38) | ALDH1A1MEN1KMT2AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |