Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 20/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 18/20 | 1.00 |
| ▸ | ALOX5AP | P20292 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103598 | 0.87 | EPHX2 (0.86) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL7541316 | 0.83 | ALOX5 (0.78) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL20103430 | 0.83 | ALOX5 (0.78) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL7542390 | 0.82 | ALOX5 (0.76) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL7547541 | 0.82 | ALOX5 (0.76) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL20103597 | 0.81 | EPHX2 (0.78) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL20103473 | 0.80 | ALOX5 (0.67) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL20103574 | 0.80 | ALOX5 (0.67) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL7541426 | 0.80 | ALOX5 (0.74) | EPHX2ALOX5ALOX5AP | |
| SCHEMBL7548473 | 0.80 | ALOX5 (0.74) | EPHX2ALOX5ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214048-A1 | DUAL INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE AND 5-LIPOXYGENASE | Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) | 2021-10-28 | — | — | WO | disclosed |
| WO-2018077898-A1 | N,N'-DIARYLUREA, N,N'-DIARYLTHIOUREA AND N,N'-DIARYLGUANIDINO COMPOUNDS FOR USE IN TREATMENT AND PREVENTION OF INFLAMMATORY DISEASE | UNIVERSITÄT INNSBRUCK (AT) | 2018-05-03 | — | — | WO | disclosed |
| EP-3315495-A1 | N,N' -DIARYLUREA, N,N' -DIARYLTHIOUREA AND N,N' -DIARYLGUANIDINO COMPOUNDS FOR USE IN TREATMENT AND PREVENTION OF INFLAMMATORY DISEASE | Universität Innsbruck (AT) | 2018-05-02 | — | — | EP | disclosed |