Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PYCR1 | P32322 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103937 | 0.80 | CYP1A2 (0.53) | MEN1KMT2AKDM4ETSHRPYCR1 | |
| SCHEMBL7158728 | 0.77 | AOC3 (0.62) | MEN1KMT2AKDM4ETSHRPYCR1 | |
| SCHEMBL24124009 | 0.73 | PYCR1 (0.47) | KDM4EPYCR1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL17110143 | 0.72 | HTR2A (0.51) | MEN1KMT2AKDM4ECYP2D6CYP2C19 | |
| SCHEMBL18532755 | 0.71 | PYCR1 (0.67) | MEN1KMT2AKDM4ETSHRPYCR1 | |
| SCHEMBL24821340 | 0.70 | CYP1A2 (0.47) | MEN1KMT2AKDM4ETSHRPYCR1 | |
| SCHEMBL14006726 | 0.70 | PYCR1 (0.56) | KDM4ETSHRPYCR1SIGMAR1TMEM97 | |
| SCHEMBL7057925 | 0.70 | SIGMAR1 (0.45) | MEN1KMT2AKDM4ENPSR1SIGMAR1 | |
| SCHEMBL6547406 | 0.69 | TAAR1 (0.48) | MEN1KMT2AKDM4EPYCR1CYP1A2 | |
| SCHEMBL7057929 | 0.69 | HTR6 (0.44) | MEN1KMT2AKDM4ETSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |