Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12441829 | 1.00 | TLR4 (0.43) | TLR4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1129322 | 0.87 | ALDH1A1 (0.44) | TLR4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL29263995 | 0.87 | ALDH1A1 (0.44) | TLR4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL15415140 | 0.82 | TLR4 (0.46) | TLR4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9977803 | 0.81 | CYP2D6 (0.34) | TLR4KMT2ACYP2D6 | |
| SCHEMBL276016 | 0.81 | TLR4 (0.51) | TLR4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2470785 | 0.81 | TLR4 (0.51) | TLR4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7733726 | 0.79 | TLR4 (0.50) | TLR4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7392059 | 0.79 | TLR4 (0.50) | TLR4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28368812 | 0.79 | TLR4 (0.50) | TLR4ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |