Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18814185 | 0.84 | ALDH1A1 (0.34) | TYMPHRH3PDE4APDE4BPDE4C | |
| SCHEMBL9073051 | 0.76 | TAAR1 (0.52) | TYMPKCNH2HSD11B1CFTR | |
| SCHEMBL8308252 | 0.74 | MEN1 (0.51) | TYMPKCNH2HSD11B1TBXAS1CYP3A4 | |
| SCHEMBL10079575 | 0.74 | PDE4D (0.35) | PDE4APDE4BPDE4CPDE4DBDKRB2 | |
| SCHEMBL8995833 | 0.74 | TDP1 (0.38) | TDP1L3MBTL1KCNH2HRH3TBXAS1 | |
| SCHEMBL11708464 | 0.72 | PTGS2 (0.55) | TBXAS1CYP19A1CYP3A4PTGS2 | |
| SCHEMBL2509554 | 0.72 | TYMP (0.50) | TYMP | |
| SCHEMBL19986675 | 0.71 | BDKRB2 (0.34) | PDE4APDE4BPDE4CPDE4DBDKRB2 | |
| SCHEMBL17056904 | 0.70 | PDE4D (0.30) | PDE4D | |
| SCHEMBL6514186 | 0.70 | PDE4D (0.30) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |