Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 4/20 | 0.41 |
| ▸ | PRKCB | P05771 | 4/20 | 0.41 |
| ▸ | PRKCH | P24723 | 4/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.41 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2281531 | 0.86 | THRA (0.44) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL3844078 | 0.84 | THRA (0.40) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL23397540 | 0.78 | ACHE (0.47) | HTR2AHTR2CTHRATHRBHTR2B | |
| SCHEMBL12827736 | 0.76 | GPR3 (0.39) | THRATHRBGPR3KAT8PPARA | |
| SCHEMBL7845549 | 0.76 | FFAR1 (0.40) | PPARA | |
| SCHEMBL12828018 | 0.76 | S1PR1 (0.38) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL19883579 | 0.74 | KCNJ1 (0.39) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL4898274 | 0.74 | HTR2A (0.55) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL30369240 | 0.74 | HTR2A (0.55) | HTR2AHTR2CDRD2SLC6A2SLC6A4 | |
| SCHEMBL4900272 | 0.74 | HTR2A (0.55) | HTR2AHTR2CDRD2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964649-B2 | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-06-21 | — | — | US | disclosed |
| US-7964649-B2 | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090253760-A1 | HYDRINDANE ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST ACTIVITY | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-10-08 | — | — | US | disclosed |
| US-20090253760-A1 | HYDRINDANE ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST ACTIVITY | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-10-08 | — | — | US | disclosed |
| EP-2099741-A2 | HYDRINDANE ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST ACTIVITY | University Of Virginia Patent Foundation (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008064320-A2 | HYDRINDANE ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST ACTIVITY | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253760-A1 | HYDRINDANE ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST ACTIVITY | S1PR1, S1PR3, S1PR2 | HTR2A 284/4885HTR2C 541/4885DRD2 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.