SCHEMBL20104372

SCHEMBL20104372

Clc1ccc2c(ccc3cnnn32)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.35
CHEK1 O14757 1/20 0.35
LIMK1 P53667 1/20 0.35
MAPK14 Q16539 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
KMO O15229 3/20 0.34
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NOS1 P29475 2/20 0.33
CUL4A Q13619 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
DYRK1A Q13627 1/20 0.33
THRB P10828 1/20 0.32
PARP15 Q460N3 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
SLC6A2 P23975 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11656139 0.66 PARP15 (0.47) CHEK1LIMK1MAPK14CLK4ALDH1A1
SCHEMBL2228619 0.64 CYP2A6 (0.50) CYP2A6KMOALDH1A1SMN1; SMN2NOS1
SCHEMBL29644361 0.62 CYP2A6 (0.77) CYP2A6ALDH1A1SMN1; SMN2NOS1DYRK1A
SCHEMBL865990 0.62 CYP2A6 (0.77) CYP2A6ALDH1A1SMN1; SMN2NOS1DYRK1A
Hydrochloric Acid SCHEMBL29200223 0.60 CYP2A6 (0.72) CYP2A6ALDH1A1SMN1; SMN2NOS1DYRK1A
SCHEMBL30027002 0.60 CYP2A6 (0.72) CYP2A6ALDH1A1SMN1; SMN2NOS1DYRK1A
SCHEMBL2473615 0.60 CYP2A6 (0.72) CYP2A6ALDH1A1SMN1; SMN2NOS1DYRK1A
SCHEMBL3660473 0.59 KMO (0.51) KMOALDH1A1SMN1; SMN2NOS1HTR2A
SCHEMBL13106151 0.59 KMO (0.51) KMOCYP11B1CYP11B2
SCHEMBL11549772 0.58 MAPT (0.65) CYP2A6KMOALDH1A1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018080065-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2018-05-03 WO disclosed