SCHEMBL2228619

SCHEMBL2228619

Clc1ccc2cnncc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.50
NOS1 P29475 2/20 0.45
DYRK1A Q13627 2/20 0.45
NR4A2 P43354 2/20 0.40
F11 P03951 1/20 0.39
AHR P35869 2/20 0.38
F7 P08709 2/20 0.38
F3 P13726 2/20 0.38
CMA1 P23946 1/20 0.38
LTA4H P09960 1/20 0.38
TP53 P04637 1/20 0.38
PDGFRB P09619 1/20 0.37
PDGFRA P16234 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 2/20 0.36
LMNA P02545 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL865990 0.76 CYP2A6 (0.77) CYP2A6NOS1DYRK1ANR4A2F11
SCHEMBL29644361 0.76 CYP2A6 (0.77) CYP2A6NOS1DYRK1ANR4A2F11
SCHEMBL28857448 0.74 ALDH1A1 (0.37) ALDH1A1
Hydrochloric Acid SCHEMBL29200223 0.74 CYP2A6 (0.72) CYP2A6NOS1DYRK1ANR4A2F11
SCHEMBL30027002 0.74 CYP2A6 (0.72) CYP2A6NOS1DYRK1ANR4A2F11
SCHEMBL2473615 0.74 CYP2A6 (0.72) CYP2A6NOS1DYRK1ANR4A2F11
SCHEMBL10976089 0.73 CYP2A6 (0.50) CYP2A6NOS1DYRK1ANR4A2F11
SCHEMBL1538404 0.73 CYP2A6 (0.50) CYP2A6NOS1DYRK1ANR4A2PDGFRB
SCHEMBL691988 0.73 PRKCZ (0.50) CYP2A6NOS1DYRK1ANR4A2PDGFRB
SCHEMBL30012364 0.73 CYP2A6 (0.50) CYP2A6NOS1DYRK1ANR4A2PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783927-B2 CONTAINING SURFACTANT FUJI PHOTO FILM, CO., LTD. (JP) 2004-08-31 US claimed
US-6423486-B1 None US disclosed
CN-110579936-B Thermally developable photosensitive material and medical film using the same 柯尼卡美能达株式会社 2023-10-27 CN disclosed
US-20210292340-A1 CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2021-09-23 US disclosed
CN-110579936-A Heat-developable photosensitive material and medical film using the same 柯尼卡美能达株式会社 2019-12-17 CN disclosed
CN-109134429-A Phthalazines ketone compounds, preparation method, pharmaceutical composition and purposes 中国科学院上海药物研究所 2019-01-04 CN disclosed
CN-107073901-A Laminated safety glass 爱克发印艺公司 2017-08-18 CN disclosed
EP-1072948-B1 Thermally processed image recording material FUJIFILM CORP (JP) 2017-07-05 EP disclosed
US-7977040-B2 Sharp images; medical diagnosis; mixture of photosensitive silver halide emulsion, organic silver salt, reducing agents and binder on support FUJIFILM CORPORATION (JP) 2011-07-12 US disclosed
EP-1637924-B1 Image forming method using photothermographic material FUJIFILM CORP (JP) 2010-07-21 EP disclosed
CN-1171846-A Hydrazide compounds useful as co-developers for black-and -white photothermographic elements IMATION CORP (US) 1998-01-28 CN disclosed
CN-1168482-A Photothermographic material and method for making FUJI PHOTO FILM CO LTD (JP) 1997-12-24 CN disclosed
EP-0805376-A2 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 1997-11-05 EP disclosed
CN-1164282-A Photothermographic material having high interlayer adhesion IMATION CORP (US) 1997-11-05 CN disclosed
CN-1164283-A Photothermographic element with reduced wood grain interference pattern IMATION CORP (US) 1997-11-05 CN disclosed
EP-0803764-A1 Photothermographic material and method for making FUJI PHOTO FILM CO., LTD. (JP) 1997-10-29 EP disclosed
CN-1155678-A Heat-developable light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1997-07-30 CN disclosed
CN-1147867-A Apparatus, system and method for processing photothermographic elements MINNESOTA MINING & MFG (US) 1997-04-16 CN disclosed
CN-1147864-A Process for manufacturing stable photothermographic elements MINNESOTA MINING & MFG (US) 1997-04-16 CN disclosed
CN-1102889-A Photothermographic elements MINNESOTA MINING & MFG (US) 1995-05-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210292340-A1 CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF LITAF, RIPK1, RIPK2 CYP2A6 4721/4885NOS1 257/4885DYRK1A 4552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.