SCHEMBL20104701

SCHEMBL20104701

C1=Nc2ccccc2C2(CCCCCCCCCC2)N1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 9/20 0.41
ADORA3 P0DMS8 1/20 0.37
PDE7B Q9NP56 1/20 0.34
KMT2A Q03164 1/20 0.32
PRCP P42785 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570230 0.84 OPRM1 (0.38) KMT2A
SCHEMBL20104700 0.75 PDE7A (0.36) PDE7AADORA3PDE7B
SCHEMBL20198617 0.74 PDE7A (0.36) PDE7AADORA3PDE7B
SCHEMBL20198618 0.74 PDE7A (0.36) PDE7AADORA3PDE7B
SCHEMBL13481074 0.71 HTR5A (0.32)
SCHEMBL17205597 0.70 CRBN (0.40) KMT2A
SCHEMBL30574138 0.69 ADORA3 (0.39) PDE7AADORA3
SCHEMBL20991112 0.69 ADORA3 (0.39) PDE7AADORA3
SCHEMBL20469074 0.69 ADORA3 (0.39) PDE7AADORA3
SCHEMBL1743215 0.69 ADORA3 (0.39) PDE7AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11195597-B2 Method and device for calculating acid dissociation constant, and program FUJITSU LIMITED (JP) 2021-12-07 US disclosed
US-20180121632-A1 METHOD AND DEVICE FOR CALCULATING ACID DISSOCIATION CONSTANT, AND PROGRAM FUJITSU LIMITED (JP) 2018-05-03 US disclosed