Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ARNT | P27540 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010493 | 0.82 | ALDH1A1 (0.42) | ALDH1A1POLBMAPTHTTMEN1 | |
| SCHEMBL20214378 | 0.80 | ALDH1A1 (0.49) | ALDH1A1POLBPDE7AMAPTHTT | |
| SCHEMBL2012871 | 0.79 | HSD17B10 (0.49) | ALDH1A1POLBPDE7AMAPTLMNA | |
| SCHEMBL14021283 | 0.76 | ALDH1A1 (0.50) | ALDH1A1POLBPDE7AMAPTHTT | |
| SCHEMBL2015323 | 0.76 | ALDH1A1 (0.57) | ALDH1A1POLBPDE7AMAPTHTT | |
| SCHEMBL29618194 | 0.75 | ALDH1A1 (0.49) | ALDH1A1POLBPDE7AMAPTHTT | |
| SCHEMBL19205982 | 0.75 | ALDH1A1 (0.49) | ALDH1A1POLBPDE7AMAPTHTT | |
| SCHEMBL588926 | 0.75 | ALDH1A1 (0.49) | ALDH1A1POLBPDE7AMAPTHTT | |
| SCHEMBL28664477 | 0.75 | ALDH1A1 (0.49) | ALDH1A1POLBPDE7AMAPTHTT | |
| SCHEMBL19461598 | 0.73 | PDE7A (0.49) | ALDH1A1POLBPDE7AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120322768-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING PROTOZOAN INFECTIONS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2012-12-20 | — | — | US | disclosed |
| WO-2011066416-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PROTOZOAN INFECTIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322768-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING PROTOZOAN INFECTIONS | PHOSPHO1, CYCS, DPM1 | ALDH1A1 2072/4885POLB 1142/4885PDE7A 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.