Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012871 | 0.82 | HSD17B10 (0.49) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL2010479 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1CYP1A2MAPT | |
| SCHEMBL2008510 | 0.80 | MEN1 (0.35) | ALDH1A1HIF1AKMT2AMEN1CYP1A2 | |
| SCHEMBL5001384 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HIF1AKMT2ACYP1A2TDP1 | |
| SCHEMBL29673195 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HIF1AKMT2ACYP1A2TDP1 | |
| SCHEMBL4297302 | 0.74 | LOXL2 (0.53) | ALDH1A1CYP1A2POLBTSHR | |
| Hydrochloric Acid SCHEMBL20766281 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HIF1AKMT2ACYP1A2TDP1 | |
| SCHEMBL20718830 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HIF1AKMT2AMEN1CYP1A2 | |
| SCHEMBL29780563 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HIF1AKMT2AMEN1CYP1A2 | |
| SCHEMBL16207595 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HIF1AKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120322768-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING PROTOZOAN INFECTIONS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2012-12-20 | — | — | US | disclosed |
| WO-2011066416-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PROTOZOAN INFECTIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322768-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING PROTOZOAN INFECTIONS | PHOSPHO1, CYCS, DPM1 | ALDH1A1 2072/4885HIF1A 2452/4885KMT2A 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.