Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393599 | 0.94 | MAPT (0.59) | MAPTHPGDRAB9AHSD17B1SMN1; SMN2 | |
| SCHEMBL2446927 | 0.83 | HSD17B10 (0.55) | L3MBTL1KMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL11965976 | 0.79 | ESR2 (0.33) | MAPTRAB9ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL9789228 | 0.78 | MAPT (0.86) | MAPTHPGDRAB9AHSD17B1SMN1; SMN2 | |
| SCHEMBL12869527 | 0.78 | STS (0.45) | MAPTHPGDRAB9ALMNAKMT2A | |
| SCHEMBL18823077 | 0.77 | ELANE (0.51) | MAPTRAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL10541266 | 0.77 | L3MBTL1 (0.56) | MAPTHPGDRAB9AHSD17B1SMN1; SMN2 | |
| SCHEMBL197130 | 0.77 | MAPT (0.80) | MAPTHPGDRAB9AHSD17B1SMN1; SMN2 | |
| SCHEMBL11441494 | 0.77 | MAPT (0.80) | MAPTHPGDRAB9AHSD17B1SMN1; SMN2 | |
| SCHEMBL11306924 | 0.76 | MAPT (0.61) | MAPTHPGDRAB9AHSD17B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2977428-B1 | POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2018-05-02 | — | — | EP | disclosed |