SCHEMBL2446927

SCHEMBL2446927

C=COc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.55
RXRA P19793 3/20 0.49
ALDH1A1 P00352 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
BCL2L1 Q07817 1/20 0.48
BAD Q92934 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
RARB P10826 5/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
RXRB P28702 2/20 0.44
KMT2A Q03164 2/20 0.44
PARP15 Q460N3 1/20 0.44
PARP10 Q53GL7 1/20 0.44
SRD5A2 P31213 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2446002 0.94 CA1 (0.54) HSD17B10ALDH1A1L3MBTL1CA1CA2
SCHEMBL2447375 0.85 XDH (0.51) ALDH1A1L3MBTL1CA1CA2RARB
SCHEMBL2447376 0.85 XDH (0.51) ALDH1A1L3MBTL1CA1CA2RARB
SCHEMBL20105017 0.83 MAPT (0.53) HSD17B10ALDH1A1L3MBTL1KMT2AMEN1
SCHEMBL12780511 0.82 HSD17B10 (0.56) HSD17B10RXRAALDH1A1BCL2L1BAD
SCHEMBL11965976 0.81 ESR2 (0.33) HSD17B10ALDH1A1TP53TSHR
SCHEMBL12869527 0.79 STS (0.45) ALDH1A1KMT2ASRD5A2MEN1
SCHEMBL738463 0.79 HSD17B10 (0.62) HSD17B10RXRAALDH1A1L3MBTL1BCL2L1
Butyl Alcohol SCHEMBL2230325 0.79 TP53 (0.53) ALDH1A1L3MBTL1CA1CA2RARB
SCHEMBL371015 0.78 ALDH1A1 (0.50) HSD17B10ALDH1A1L3MBTL1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006351-B1 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM NIPPON OIL CORP (JP) 2011-10-12 EP disclosed
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
US-7763182-B2 Liquid crystalline composition with improved adhesivity, liquid crystal film comprising the composition, and liquid crystal display device equipped with the film NIPPON OIL CORPORATION (JP) 2010-07-27 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
US-20090208673-A1 Liquid Crystalline Composition with Improved Adhesivity, Liquid Crystal Film Comprising the Composition, and Liquid Crystal Display Device Equipped with the Film NIPPON OIL CORPORATION (JP) 2009-08-20 US disclosed
EP-2006351-A9 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2009-07-01 EP disclosed
EP-2006351-A2 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2008-12-24 EP disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed