Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17461504 | 0.94 | THRB (0.49) | THRBALOX15KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20105059 | 0.93 | THRB (0.50) | THRBALOX15KMT2AMAPTNFKB1 | |
| SCHEMBL17719454 | 0.89 | THRB (0.42) | THRBALOX15KMT2AMAPTNFKB1 | |
| SCHEMBL20105058 | 0.89 | THRB (0.46) | THRBALOX15KMT2AMAPTESR1 | |
| SCHEMBL17461507 | 0.89 | THRB (0.44) | THRBALOX15KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL17719452 | 0.88 | THRB (0.51) | THRBALOX15KMT2AMAPTNFKB1 | |
| SCHEMBL17754307 | 0.88 | THRB (0.44) | THRBALOX15KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21556860 | 0.88 | ADRB2 (0.47) | THRBALOX15KMT2AMAPTNFKB1 | |
| SCHEMBL20414524 | 0.88 | THRB (0.44) | THRBALOX15KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21003764 | 0.87 | THRB (0.45) | THRBKMT2AMAPTSMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2977428-B1 | POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2018-05-02 | — | — | EP | disclosed |