SCHEMBL17754307

SCHEMBL17754307

C=CC(=O)Oc1ccc(CCC(=O)Oc2ccc(-c3ccc(OC(=O)C(=C)C)cc3)cc2)cc1OC(=O)C=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.44
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.39
CCR5 P51681 3/20 0.36
ALOX15 P16050 2/20 0.36
AKR1C3 P42330 2/20 0.36
ELANE P08246 1/20 0.36
PTGS1 P23219 1/20 0.36
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAOA P21397 1/20 0.35
SLC6A2 P23975 1/20 0.35
RAB9A P51151 1/20 0.35
SLC6A3 Q01959 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20414524 1.00 THRB (0.44) THRBKMT2AMAPTCCR5ALOX15
SCHEMBL17754358 0.95 KMT2A (0.41) THRBKMT2AMAPTCCR5ALOX15
SCHEMBL17461533 0.94 THRB (0.47) THRBKMT2AMAPTCCR5ALOX15
SCHEMBL17461532 0.94 THRB (0.47) THRBKMT2AMAPTCCR5ALOX15
SCHEMBL19524234 0.93 KMT2A (0.45) THRBKMT2AMAPTCCR5AKR1C3
SCHEMBL17433321 0.93 THRB (0.48) THRBKMT2AMAPTCCR5ALOX15
SCHEMBL18324427 0.93 THRB (0.42) THRBKMT2AMAPTCCR5ALOX15
SCHEMBL20414523 0.92 KMT2A (0.47) KMT2AMAPTCCR5ALOX15AKR1C3
SCHEMBL17461515 0.92 KMT2A (0.42) THRBKMT2AMAPTCCR5AKR1C3
SCHEMBL20419792 0.92 ADRB2 (0.43) THRBKMT2AMAPTCCR5ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used DIC CORPORATION (JP) 2023-09-19 US disclosed
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used DIC CORPORATION (JP) 2023-09-19 US disclosed
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2023-05-02 US disclosed
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2023-05-02 US disclosed
US-11174217-B2 Polymerizable compound and liquid crystal composition DIC CORPORATION (JP) 2021-11-16 US disclosed
US-20210214299-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2021-07-15 US disclosed
US-20200308488-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT IN WHICH THE COMPOUND IS USED DIC CORPORATION (JP) 2020-10-01 US disclosed
US-20190144750-A1 POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME DIC CORPORATION (JP) 2019-05-16 US disclosed
US-20180208846-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME DIC CORPORATION (JP) 2018-07-26 US disclosed
US-20180208846-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME DIC CORPORATION (JP) 2018-07-26 US disclosed
US-20170327742-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-11-16 US disclosed
US-20170327742-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-11-16 US disclosed
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME DIC CORPORATION (JP) 2016-05-19 US disclosed
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME DIC CORPORATION (JP) 2016-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME RCC1, LPXN, SMC4 THRB 4879/4885KMT2A 2308/4885MAPT 66/4885
US-11760934-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used SFXN1, SFXN3, SIK3 THRB 3014/4885KMT2A 3540/4885MAPT 4455/4885
US-11174217-B2 Polymerizable compound and liquid crystal composition PI4KA, PKN2, KCNH3 THRB 4768/4885KMT2A 1009/4885MAPT 2603/4885
US-20210214299-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME SKP1, PKN1, KTN1 THRB 4727/4885KMT2A 1564/4885MAPT 1484/4885
US-20200308488-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT IN WHICH THE COMPOUND IS USED SFXN1, SFXN3, SIK3 THRB 3014/4885KMT2A 3540/4885MAPT 4455/4885
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same SKP1, PKN1, KTN1 THRB 4727/4885KMT2A 1564/4885MAPT 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.