SCHEMBL2010659

SCHEMBL2010659

CO[SiH](OC)C(C)CCc1ccccc1I

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43
IDO1 P14902 2/20 0.38
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR7 P34969 1/20 0.31
HTR6 P50406 1/20 0.31
G6PD P11413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639328 0.79 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL3338998 0.79 TSHR (0.42) G6PD
SCHEMBL4368919 0.76 TAAR1 (0.54) TAAR1IDO1SLC6A2SLC6A4SLC6A3
SCHEMBL623309 0.73 SLC6A2 (0.61) TAAR1IDO1SLC6A2SLC6A4SLC6A3
SCHEMBL30520633 0.73 SLC6A2 (0.61) TAAR1IDO1SLC6A2SLC6A4SLC6A3
SCHEMBL3243108 0.73 TAAR1 (0.50) TAAR1IDO1SLC6A2SLC6A4SLC6A3
SCHEMBL1031553 0.72 GABRA1 (0.34) TAAR1IDO1SLC6A2SLC6A4SLC6A3
SCHEMBL29178138 0.72 TAAR1 (0.48) TAAR1IDO1ATML3MBTL1HTR2A
SCHEMBL1637621 0.70 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3L3MBTL1
SCHEMBL10996592 0.66 TAAR1 (0.50) TAAR1IDO1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1445288-B1 Organic-inorganic composite particle and process for preparation thereof ROHM & HAAS (US) 2017-03-08 EP disclosed
US-8906982-B2 Coating with improved hiding compositions prepared therewith, and processes for the preparation thereof ROHM AND HAAS COMPANY (US) 2014-12-09 US disclosed
US-8822569-B2 Composite particles ROHM AND HAAS COMPANY (US) 2014-09-02 US disclosed
US-7960026-B2 Organic-inorganic composite particle and process for preparation thereof ROHM AND HAAS COMPANY (US) 2011-06-14 US disclosed
EP-2050796-B1 Coating with improved hiding, compositions prepared therewith, and processes for the preparation thereof ROHM & HAAS (US) 2010-09-22 EP disclosed
US-20090306278-A1 Coating with improved hiding compositions prepared therewith, and processes for the preparation thereof ROHM AND HAAS COMPANY 2009-12-10 US disclosed
EP-2050796-A1 Coating with improved hiding, compositions prepared therewith, and processes for the preparation thereof Rohm and Haas Company (US) 2009-04-22 EP disclosed
US-7488534-B2 Organic-inorganic composite particle and process for preparation thereof ROHM AND HAAS COMPANY (US) 2009-02-10 US disclosed
US-20090017304-A1 Organic-inorganic composite particle and process for preparation thereof KOLLER ANNE DENISE 2009-01-15 US disclosed
EP-1398333-B1 Polymer particles having select pendant groups and composition prepared therefrom ROHM & HAAS (US) 2008-07-09 EP disclosed
US-20060223911-A1 Composite particles ROHM AND HAAS COMPANY 2006-10-05 US disclosed
US-7081488-B2 Coating with improved hiding, compositions prepared therewith, and processes for the preparation thereof ROHM AND HAAS COMPANY (US) 2006-07-25 US disclosed
US-20050009954-A1 Aqueous polymer composition ROHM AND HAAS COMPANY 2005-01-13 US disclosed
EP-1496091-A1 Aqueous polymer composition ROHM AND HAAS COMPANY (US) 2005-01-12 EP disclosed
EP-1445288-A2 Organic-inorganic composite particle and process for preparation thereof ROHM AND HAAS COMPANY (US) 2004-08-11 EP disclosed
US-20040151910-A1 Organic-inorganic composite particle and process for preparation thereof ROHM AND HAAS COMPANY 2004-08-05 US disclosed
US-20040054063-A1 Polymer particles having select pendant groups and composition prepared therefrom ROHM AND HAAS COMPANY 2004-03-18 US disclosed
EP-1398333-A1 Polymer particles having select pendant groups and composition prepared therefrom ROHM AND HAAS COMPANY (US) 2004-03-17 EP disclosed
US-20030018103-A1 Coating with improved hiding, compositions prepared therewith, and processes for the preparation thereof ROHM AND HAAS COMPANY 2003-01-23 US disclosed
EP-1273636-A2 Coating with improved hiding compositions prepared therewith, and processes for the preparation thereof ROHM AND HAAS COMPANY (US) 2003-01-08 EP disclosed