Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4368919 | 0.83 | TAAR1 (0.54) | TAAR1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL623309 | 0.80 | SLC6A2 (0.61) | TAAR1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL30520633 | 0.80 | SLC6A2 (0.61) | TAAR1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL853320 | 0.79 | TAAR1 (0.43) | TAAR1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL19415512 | 0.79 | TAAR1 (0.43) | TAAR1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL16054294 | 0.78 | TAAR1 (0.48) | TAAR1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL14286302 | 0.78 | TYR (0.47) | TYRSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL1716142 | 0.78 | TAAR1 (0.52) | TAAR1TYRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2486648 | 0.78 | TYR (0.61) | TAAR1TYRIDO1SLC6A4CYP2D6 | |
| SCHEMBL10996592 | 0.76 | TAAR1 (0.50) | TAAR1HTR2AHTR2CHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243543-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2014-08-28 | — | — | US | disclosed |
| US-8716507-B2 | Iron(II) catalysts containing diimino-diphosphine tetradentate ligands and their synthesis | THE GOVERNING COUNCIL OF UNIVERSITY OF TORONTO (CA) | 2014-05-06 | — | — | US | disclosed |
| EP-2210612-A2 | Macrocyclic antagonists of the motilin receptor | Tranzyme Pharma Inc. (CA) | 2010-07-28 | — | — | EP | disclosed |
| US-20100145087-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145087-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | FTH1, FECH, IDH1 | TAAR1 291/4885TYR 743/4885HTR2A 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.