Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20106757 | 0.89 | GPR119 (0.44) | GPR119 | |
| SCHEMBL15507268 | 0.82 | GPR119 (0.55) | GPR119 | |
| SCHEMBL19584795 | 0.79 | RORC (0.45) | GPR119 | |
| SCHEMBL20106999 | 0.76 | CYP3A4 (0.32) | — | |
| SCHEMBL25924019 | 0.76 | — | — | |
| SCHEMBL18357595 | 0.74 | EPHX2 (0.42) | DDB1CRBN | |
| SCHEMBL21089246 | 0.74 | CACNA1H (0.33) | GPR119 | |
| SCHEMBL21088402 | 0.74 | — | — | |
| SCHEMBL6114687 | 0.73 | CHRM2 (0.45) | DDB1CRBN | |
| SCHEMBL16122957 | 0.73 | USP2 (0.43) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532459-B1 | LSD1 INHIBITORS AND MEDICAL USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |
| WO-2018081343-A1 | LSD1 INHIBITORS AND MEDICAL USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2018-05-03 | — | — | WO | disclosed |