Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368275 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4ELMNADHODH | |
| SCHEMBL20106759 | 0.85 | KDM4E (0.34) | ALDH1A1KMT2AKDM4ELMNADHODH | |
| SCHEMBL20088555 | 0.78 | KDM4E (0.36) | ALDH1A1KMT2AKDM4ELMNADHODH | |
| SCHEMBL20088528 | 0.78 | KDM4E (0.36) | ALDH1A1KMT2AKDM4ELMNADHODH | |
| SCHEMBL20106937 | 0.69 | HAVCR2 (0.33) | PDE10A | |
| SCHEMBL20088554 | 0.69 | KDM4E (0.33) | ALDH1A1KMT2AKDM4ELMNADHODH | |
| SCHEMBL20094672 | 0.66 | TRPA1 (0.52) | — | |
| SCHEMBL20088513 | 0.66 | KDM4E (0.41) | ALDH1A1KMT2AKDM4ELMNAPDE10A | |
| SCHEMBL20094352 | 0.66 | KDM4E (0.41) | ALDH1A1KMT2AKDM4ELMNAPDE10A | |
| SCHEMBL20088561 | 0.64 | PDE10A (0.38) | KMT2AKDM4ELMNAPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080917-A1 | FUSED BICYLIC PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |