Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19558559 | 1.00 | OPRM1 (0.34) | OPRM1OPRD1OPRK1MAPK1SMN1; SMN2 | |
| SCHEMBL18358200 | 1.00 | OPRM1 (0.34) | OPRM1OPRD1OPRK1MAPK1SMN1; SMN2 | |
| SCHEMBL18358221 | 1.00 | OPRM1 (0.34) | OPRM1OPRD1OPRK1MAPK1SMN1; SMN2 | |
| SCHEMBL18358210 | 1.00 | OPRM1 (0.34) | OPRM1OPRD1OPRK1MAPK1SMN1; SMN2 | |
| SCHEMBL18358230 | 1.00 | OPRM1 (0.34) | OPRM1OPRD1OPRK1MAPK1SMN1; SMN2 | |
| SCHEMBL18358211 | 0.91 | POLB (0.34) | OPRM1OPRD1OPRK1MAPK1GAA | |
| SCHEMBL19558558 | 0.91 | POLB (0.34) | OPRM1OPRD1OPRK1MAPK1GAA | |
| SCHEMBL18358208 | 0.91 | POLB (0.34) | OPRM1OPRD1OPRK1MAPK1GAA | |
| SCHEMBL21048292 | 0.87 | PPM1B (0.32) | LMNA | |
| SCHEMBL20456365 | 0.87 | L3MBTL1 (0.49) | OPRK1GAAPOLBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087592-A1 | ENZYMATIC PROCESSES FOR THE PREPARATION OF (±)-2-(DIFLUOROMETHYL)-1-(ALKOXYCARBONYL)-CYCLOPROPANECARBOXYLIC ACID AND (±)-2-(VINYL)-1-(ALKOXYCARBONYL)-CYCLOPROPANECARBOXYLIC ACID | ABBVIE INC. | 2021-03-25 | — | — | US | disclosed |
| EP-3315497-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING CYCLOPROPANE CARBOXYLIC ACID COMPOUND | Central Glass Co., Ltd. (JP) | 2018-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087592-A1 | ENZYMATIC PROCESSES FOR THE PREPARATION OF (±)-2-(DIFLUOROMETHYL)-1-(ALKOXYCARBONYL)-CYCLOPROPANECARBOXYLIC ACID AND (±)-2-(VINYL)-1-(ALKOXYCARBONYL)-CYCLOPROPANECARBOXYLIC ACID | CTRL, DNPEP, CPN1 | OPRM1 3055/4885OPRD1 3449/4885OPRK1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.