Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358211 | 1.00 | POLB (0.34) | POLBALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL18358208 | 1.00 | POLB (0.34) | POLBALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL20467778 | 0.92 | MAPK1 (0.33) | POLBOPRM1OPRD1OPRK1MAPK1 | |
| SCHEMBL20107144 | 0.91 | OPRM1 (0.34) | POLBOPRM1OPRD1OPRK1MAPK1 | |
| SCHEMBL18358200 | 0.91 | OPRM1 (0.34) | POLBOPRM1OPRD1OPRK1MAPK1 | |
| SCHEMBL18358221 | 0.91 | OPRM1 (0.34) | POLBOPRM1OPRD1OPRK1MAPK1 | |
| SCHEMBL18358230 | 0.91 | OPRM1 (0.34) | POLBOPRM1OPRD1OPRK1MAPK1 | |
| SCHEMBL19558559 | 0.91 | OPRM1 (0.34) | POLBOPRM1OPRD1OPRK1MAPK1 | |
| SCHEMBL18358210 | 0.91 | OPRM1 (0.34) | POLBOPRM1OPRD1OPRK1MAPK1 | |
| SCHEMBL20107357 | 0.90 | POLB (0.31) | POLBOPRM1OPRD1OPRK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793540-B2 | Method for producing fluorine-containing cyclopropane carboxylic acid compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2020-10-06 | — | — | US | disclosed |
| US-10450291-B2 | Method for producing fluorine-containing cyclopropane carboxylic acid compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2019-10-22 | — | — | US | disclosed |
| US-10316338-B1 | Enzymatic process for the preparation of (1S,2R)-2-(difluoromethyl)-1-(propoxycarbonyl)cyclopropanecarboxylic acid | ABB VIE INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20180186763-A1 | Method for Producing Fluorine-Containing Cyclopropane Carboxylic Acid Compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2018-07-05 | — | — | US | disclosed |
| US-9809534-B1 | Difluoroalkylcyclopropyl amino acids and esters, and syntheses thereof | ABBVIE INC. (US) | 2017-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793540-B2 | Method for producing fluorine-containing cyclopropane carboxylic acid compound | PFAS, FDPS, CYP2F1 | POLB 1943/4885ALDH1A1 996/4885OPRM1 2386/4885 |
| US-20180186763-A1 | Method for Producing Fluorine-Containing Cyclopropane Carboxylic Acid Compound | PFAS, FDPS, FIBP | POLB 2121/4885ALDH1A1 1093/4885OPRM1 2554/4885 |
| US-10450291-B2 | Method for producing fluorine-containing cyclopropane carboxylic acid compound | PFAS, FDPS, FIBP | POLB 2121/4885ALDH1A1 1093/4885OPRM1 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.