Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25670460 | 0.90 | CYP3A4 (0.31) | CYP3A4GAA | |
| SCHEMBL6780032 | 0.85 | ALDH1A1 (0.31) | CYP3A4GAA | |
| SCHEMBL9306932 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL20107503 | 0.75 | CTSA (0.36) | — | |
| SCHEMBL20107459 | 0.74 | LAP3 (0.34) | LAP3 | |
| SCHEMBL17677605 | 0.74 | — | — | |
| SCHEMBL25670440 | 0.72 | LAP3 (0.33) | LAP3 | |
| SCHEMBL25670414 | 0.70 | — | — | |
| SCHEMBL8659098 | 0.69 | CYP3A4 (0.33) | CYP3A4GAAMEN1KMT2ALAP3 | |
| SCHEMBL18535411 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667866-B2 | Phosphorous containing compounds and uses thereof | AFTON CHEMICAL CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667866-B2 | Phosphorous containing compounds and uses thereof | AFTON CHEMICAL CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210355408-A1 | Phosphorous Containing Compounds and Uses Thereof | AFTON CHEMICAL CORP (US) | 2021-11-18 | — | — | US | disclosed |
| US-11066619-B2 | Phosphorous containing compounds and uses thereof | AFTON CHEMICAL CORPORATION (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200056114-A1 | Phosphorous Containing Compounds and Uses Thereof | AFTON CHEMICAL CORP (US) | 2020-02-20 | — | — | US | disclosed |
| WO-2018081822-A1 | PHOSPHOROUS CONTAINING COMPOUNDS AND USES THEREOF | AFTON CHEMICAL CORPORATION (US) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355408-A1 | Phosphorous Containing Compounds and Uses Thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885GAA 3912/4885MEN1 1894/4885 |
| US-20200056114-A1 | Phosphorous Containing Compounds and Uses Thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885GAA 3912/4885MEN1 1894/4885 |
| US-11667866-B2 | Phosphorous containing compounds and uses thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885GAA 3912/4885MEN1 1894/4885 |
| US-11066619-B2 | Phosphorous containing compounds and uses thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885GAA 3912/4885MEN1 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.