Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628174 | 1.00 | KMT2A (0.58) | KMT2AMEN1ALDH1A1POLBTP53 | |
| SCHEMBL12628961 | 0.96 | KMT2A (0.53) | KMT2AMEN1ALDH1A1POLBTP53 | |
| SCHEMBL2015653 | 0.96 | KMT2A (0.55) | KMT2AMEN1ALDH1A1POLBTP53 | |
| SCHEMBL12628292 | 0.96 | KMT2A (0.55) | KMT2AMEN1ALDH1A1POLBTP53 | |
| SCHEMBL2012438 | 0.96 | KMT2A (0.53) | KMT2AMEN1ALDH1A1POLBTP53 | |
| SCHEMBL12628159 | 0.92 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL2011504 | 0.92 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL2017811 | 0.90 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL12628946 | 0.90 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1POLBTSHR | |
| SCHEMBL12628167 | 0.90 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |