Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628961 | 1.00 | KMT2A (0.53) | KMT2AALDH1A1MEN1POLBTP53 | |
| SCHEMBL12628292 | 0.96 | KMT2A (0.55) | KMT2AALDH1A1MEN1POLBTP53 | |
| SCHEMBL2010853 | 0.96 | KMT2A (0.58) | KMT2AALDH1A1MEN1POLBTP53 | |
| SCHEMBL12628174 | 0.96 | KMT2A (0.58) | KMT2AALDH1A1MEN1POLBTP53 | |
| SCHEMBL2015653 | 0.96 | KMT2A (0.55) | KMT2AALDH1A1MEN1POLBTP53 | |
| SCHEMBL12628159 | 0.92 | ALDH1A1 (0.54) | KMT2AALDH1A1MEN1PKMFKBP1A | |
| SCHEMBL2011504 | 0.92 | ALDH1A1 (0.54) | KMT2AALDH1A1MEN1PKMFKBP1A | |
| SCHEMBL12628946 | 0.90 | ALDH1A1 (0.51) | KMT2AALDH1A1MEN1POLBTSHR | |
| SCHEMBL2015115 | 0.90 | ALDH1A1 (0.51) | KMT2AALDH1A1MEN1POLBTSHR | |
| SCHEMBL2011582 | 0.90 | ALDH1A1 (0.60) | KMT2AALDH1A1MEN1POLBFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |