Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628159 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KMT2ARAB9AUSP2HPGD | |
| SCHEMBL2011582 | 0.92 | ALDH1A1 (0.60) | ALDH1A1KMT2AFKBP1AMEN1 | |
| SCHEMBL2012438 | 0.92 | KMT2A (0.53) | ALDH1A1KMT2AFKBP1AMEN1PKM | |
| SCHEMBL2012792 | 0.92 | ALDH1A1 (0.55) | ALDH1A1KMT2ARAB9AMEN1GAA | |
| SCHEMBL2017637 | 0.92 | ALDH1A1 (0.66) | ALDH1A1KMT2ARAB9AMEN1PKM | |
| SCHEMBL12629084 | 0.92 | ALDH1A1 (0.66) | ALDH1A1KMT2ARAB9AMEN1PKM | |
| SCHEMBL12629080 | 0.92 | ALDH1A1 (0.60) | ALDH1A1KMT2AFKBP1AMEN1 | |
| SCHEMBL12628174 | 0.92 | KMT2A (0.58) | ALDH1A1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL2013800 | 0.92 | ALDH1A1 (0.52) | ALDH1A1KMT2ARAB9AUSP2HPGD | |
| SCHEMBL12628292 | 0.92 | KMT2A (0.55) | ALDH1A1KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |