Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108681 | 0.79 | PTGS2 (0.47) | MEN1ALDH1A1MAPTKMT2AIDO1 | |
| SCHEMBL16014751 | 0.78 | IDO1 (0.50) | MEN1KMT2AIDO1RORC | |
| SCHEMBL15544520 | 0.67 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AIDO1 | |
| SCHEMBL6474667 | 0.66 | MEN1 (0.75) | MEN1ALDH1A1MAPTKMT2AIDO1 | |
| SCHEMBL17601523 | 0.66 | IDO1 (0.65) | MEN1ALDH1A1MAPTKMT2AIDO1 | |
| SCHEMBL30623277 | 0.66 | IDO1 (0.65) | MEN1ALDH1A1MAPTKMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL27827876 | 0.65 | MEN1 (0.73) | MEN1ALDH1A1MAPTKMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL27827875 | 0.65 | IDO1 (0.63) | MEN1ALDH1A1MAPTKMT2AIDO1 | |
| SCHEMBL20535682 | 0.63 | LMNA (0.56) | MEN1ALDH1A1MAPTKMT2AIDO1 | |
| SCHEMBL12459282 | 0.63 | LMNA (0.56) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |