Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16014751 | 0.81 | IDO1 (0.50) | PTGS2MEN1KMT2AIDO1 | |
| SCHEMBL20108682 | 0.79 | MEN1 (0.40) | MAPTMEN1ALDH1A1KMT2AIDO1 | |
| SCHEMBL23193681 | 0.74 | RORC (0.59) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20108664 | 0.73 | GABRP (0.41) | PTGS2ALDH1A1 | |
| SCHEMBL3074944 | 0.71 | ALDH1A1 (0.70) | PTGS2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL23193407 | 0.70 | APP (0.37) | PTGS2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL15544520 | 0.69 | MEN1 (0.48) | MAPTMEN1ALDH1A1KMT2AIDO1 | |
| SCHEMBL23193410 | 0.69 | RORC (0.54) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6474667 | 0.69 | MEN1 (0.75) | MAPTMEN1ALDH1A1KMT2AIDO1 | |
| SCHEMBL30623277 | 0.69 | IDO1 (0.65) | MAPTMEN1ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |