Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108837

SCHEMBL20108837

SCHEMBL20108837

O=P(c1ccccc1)(c1ccccc1)c1c2ccccc2c(-c2ccc3ccc4c(-c5ccc6ccc7cccnc7c6n5)ccc5ccc2c3c54)c2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.34
▸ KDM4E B2RXH2 3/20 0.34
▸ MAPT P10636 3/20 0.34
▸ SMN1; SMN2 Q16637 3/20 0.34
▸ CCR1 P32246 2/20 0.34
▸ CCR5 P51681 2/20 0.34
▸ CCR8 P51685 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ ALOX15 P16050 2/20 0.34
▸ TSHR P16473 2/20 0.34
▸ HTT P42858 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ GMNN O75496 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ MMP2 P08253 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ MMP9 P14780 1/20 0.34
▸ NFKB1 P19838 1/20 0.34
▸ MMP8 P22894 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108901 0.94 CCR1 (0.33) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108833 0.86 CCR1 (0.41) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108838 0.85 LMNA (0.36) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108870 0.85 LMNA (0.36) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108836 0.84 LMNA (0.37) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108869 0.84 MMP2 (0.36) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108854 0.80 TOP1 (0.38) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108840 0.79 LMNA (0.41) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108886 0.79 MMP2 (0.33) LMNAKDM4EMAPTSMN1; SMN2CCR1
SCHEMBL20108856 0.79 TOP1 (0.33) LMNAKDM4EMAPTSMN1; SMN2CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX LMNA 3418/4885KDM4E 2220/4885MAPT 708/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX LMNA 3418/4885KDM4E 2220/4885MAPT 708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.