Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108852

SCHEMBL20108852

SCHEMBL20108852

O=P(c1ccccc1)(c1ccccc1)c1ccc2cc(-c3ccc(-c4ccc5ccc6cccnc6c5n4)cc3)ccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 7/20 0.41
▸ TDP1 Q9NUW8 2/20 0.39
▸ MMP2 P08253 2/20 0.39
▸ CCR1 P32246 2/20 0.39
▸ CCR5 P51681 2/20 0.39
▸ CCR8 P51685 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ GMNN O75496 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ HSP90AA1 P07900 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ MMP9 P14780 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ MMP8 P22894 1/20 0.39
▸ THPO P40225 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17451965 0.96 TOP1 (0.42) TOP1TDP1MMP2CCR1CCR5
SCHEMBL19009622 0.94 TDP1 (0.42) TOP1TDP1MMP2CCR1CCR5
SCHEMBL17403770 0.92 MMP2 (0.46) TOP1TDP1MMP2CCR1CCR5
SCHEMBL20108882 0.90 PARP1 (0.40) TOP1CYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL20108874 0.89 TOP1 (0.38) TOP1TDP1MMP2CCR1CCR5
SCHEMBL20108842 0.89 TOP1 (0.36) TOP1TDP1MMP2CCR1CCR5
SCHEMBL20108853 0.88 TOP1 (0.38) TOP1TDP1MMP2CCR1CCR5
SCHEMBL30627043 0.86 CCR1 (0.43) TOP1TDP1MMP2CCR1CCR5
SCHEMBL29473314 0.86 CCR1 (0.43) TOP1TDP1MMP2CCR1CCR5
SCHEMBL21247533 0.86 CCR1 (0.43) TOP1TDP1MMP2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX TOP1 2172/4885TDP1 2177/4885MMP2 2294/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX TOP1 2172/4885TDP1 2177/4885MMP2 2294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.