Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18386212 | 0.84 | LMNA (0.38) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL20390481 | 0.83 | MEN1 (0.59) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL12230266 | 0.80 | MEN1 (0.40) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL2005244 | 0.78 | LMNA (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL18386206 | 0.78 | MAPT (0.38) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL16867351 | 0.69 | MEN1 (0.65) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL12893718 | 0.68 | MAPT (0.67) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL12410766 | 0.66 | MAPT (0.46) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL14048651 | 0.66 | LMNA (0.56) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL8498493 | 0.66 | MEN1 (0.48) | MEN1LMNAMAPTTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964361-B2 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090281279-A1 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-12 | — | — | US | disclosed |
| US-7408062-B2 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2008-08-05 | — | — | US | disclosed |
| US-20070243527-A9 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE MELLON UNIVERSITY | 2007-10-18 | — | — | US | disclosed |
| US-6686145-B1 | IMPARTING FLUORESCENT PROPERTIES TO TARGET MATERIALS BY COVALENT AND NONCOVALENT ASSOCIATION | CARNEGIE MELLON UNIVERSITY | 2004-02-03 | — | — | US | disclosed |
| US-20030224391-A1 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY | 2003-12-04 | — | — | US | disclosed |
| EP-1042407-B1 | RIGIDIZED TRIMETHINE CYANINE DYES | UNIV CARNEGIE MELLON (US) | 2001-09-12 | — | — | EP | disclosed |
| US-6133445-A | USEFUL FOR IMPARTING FLUORESCENT PROPERTIES TO TARGET MATERIALS | CARNEGIE MELLON UNIVERSITY (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1042407-A1 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE-MELLON UNIVERSITY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031181-A1 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE MELLON UNIVERSITY (US) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070243527-A9 | RIGIDIZED TRIMETHINE CYANINE DYES | SIGMAR1, CBR1, NR0B1 | MEN1 3950/4885LMNA 3893/4885MAPT 4578/4885 |
| US-20090281279-A1 | Rigidized trimethine cyanine dyes | CD47, TLN1, TPM4 | MEN1 3776/4885LMNA 1516/4885MAPT 2136/4885 |
| US-20030224391-A1 | Rigidized trimethine cyanine dyes | CBR1, TH, CBR3 | MEN1 4371/4885LMNA 3068/4885MAPT 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.