Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108873

SCHEMBL20108873

SCHEMBL20108873

O=P(c1ccccc1)(c1ccccc1)c1ccc2c(-c3ccc4ccccc4c3)c3cc(-c4ccc5ccc6cccnc6c5n4)ccc3c(-c3ccc4ccccc4c3)c2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 6/20 0.36
▸ NOS1 P29475 1/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ SIRT2 Q8IXJ6 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ GLO1 Q04760 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ GMNN O75496 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33
▸ MMP2 P08253 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ MMP9 P14780 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108844 0.97 TOP1 (0.37) TOP1NOS1TDP1SIRT2MEN1
SCHEMBL20108888 0.94 SIRT2 (0.33) TOP1NOS1TDP1SIRT2MEN1
SCHEMBL20108845 0.94 TOP1 (0.37) TOP1TDP1KDM4EGMNNLMNA
SCHEMBL20108835 0.91 TOP1 (0.38) TOP1TDP1KDM4EGMNNLMNA
SCHEMBL20108843 0.91 TOP1 (0.38) TOP1TDP1KDM4EGMNNLMNA
SCHEMBL20108893 0.89 TRPV1 (0.37) TOP1TDP1KDM4EGMNNLMNA
SCHEMBL20108853 0.89 TOP1 (0.38) TOP1TDP1MEN1KMT2AGLO1
SCHEMBL20108892 0.88 TOP1 (0.37) TOP1TDP1SIRT2KDM4EGMNN
SCHEMBL20108883 0.86 TOP1 (0.35) TOP1TDP1SIRT2KDM4EGMNN
SCHEMBL20108874 0.86 TOP1 (0.38) TOP1TDP1SIRT2KDM4EGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX TOP1 2172/4885NOS1 1081/4885TDP1 2177/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX TOP1 2172/4885NOS1 1081/4885TDP1 2177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.