Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108888

SCHEMBL20108888

SCHEMBL20108888

O=P(c1ccncc1)(c1ccncc1)c1ccc2c(-c3ccc4ccccc4c3)c3cc(-c4ccc5ccc6cccnc6c5n4)ccc3c(-c3ccc4ccccc4c3)c2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIRT2 Q8IXJ6 3/20 0.33
▸ MAPK9 P45984 3/20 0.33
▸ MAPK10 P53779 3/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ CYP17A1 P05093 1/20 0.33
▸ CYP19A1 P11511 1/20 0.33
▸ CYP11B1 P15538 1/20 0.33
▸ CYP11B2 P19099 1/20 0.33
▸ NOS1 P29475 1/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ GLO1 Q04760 1/20 0.32
▸ TOP1 P11387 2/20 0.32
▸ CDK2 P24941 1/20 0.32
▸ GSK3B P49841 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108873 0.94 TOP1 (0.36) SIRT2KDM4ECYP2C9CYP17A1CYP19A1
SCHEMBL20108844 0.91 TOP1 (0.37) SIRT2KDM4ECYP2C9L3MBTL1CYP17A1
SCHEMBL20108845 0.88 TOP1 (0.37) KDM4EL3MBTL1TDP1TOP1GMNN
SCHEMBL20108835 0.85 TOP1 (0.38) KDM4EL3MBTL1TDP1TOP1GMNN
SCHEMBL20108843 0.85 TOP1 (0.38) KDM4EL3MBTL1TDP1TOP1GMNN
SCHEMBL13808793 0.84 CCR1 (0.42) KDM4ECYP2C9L3MBTL1NPC1RAB9A
SCHEMBL20108893 0.83 TRPV1 (0.37) KDM4ECYP2C9L3MBTL1NPC1CYP17A1
SCHEMBL20108853 0.83 TOP1 (0.38) KDM4ECYP2C9L3MBTL1TDP1MEN1
SCHEMBL10353276 0.82 CYP17A1 (0.41) KDM4EL3MBTL1NPC1RAB9ACYP17A1
SCHEMBL19009622 0.82 TDP1 (0.42) SIRT2KDM4ECYP17A1CYP19A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX SIRT2 1420/4885MAPK9 2084/4885MAPK10 3661/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX SIRT2 1420/4885MAPK9 2084/4885MAPK10 3661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.