Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108844

SCHEMBL20108844

SCHEMBL20108844

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc3c(-c4ccc5ccccc5c4)c4cc(-c5ccc6ccc7cccnc7c6n5)ccc4c(-c4ccc5ccccc5c4)c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 3/20 0.37
▸ SIRT2 Q8IXJ6 2/20 0.35
▸ CYP17A1 P05093 1/20 0.35
▸ CYP19A1 P11511 1/20 0.35
▸ CYP11B1 P15538 1/20 0.35
▸ CYP11B2 P19099 1/20 0.35
▸ NOS1 P29475 1/20 0.34
▸ TDP1 Q9NUW8 2/20 0.33
▸ CCR1 P32246 2/20 0.33
▸ CCR5 P51681 2/20 0.33
▸ CCR8 P51685 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ GLO1 Q04760 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ GMNN O75496 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33
▸ MMP2 P08253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108873 0.97 TOP1 (0.36) TOP1SIRT2CYP17A1CYP19A1CYP11B1
SCHEMBL20108843 0.94 TOP1 (0.38) TOP1TDP1CCR1CCR5CCR8
SCHEMBL20108835 0.94 TOP1 (0.38) TOP1TDP1CCR1CCR5CCR8
SCHEMBL20108888 0.91 SIRT2 (0.33) TOP1SIRT2CYP17A1CYP19A1CYP11B1
SCHEMBL20108845 0.91 TOP1 (0.37) TOP1TDP1CCR1CCR5CCR8
SCHEMBL20108892 0.91 TOP1 (0.37) TOP1SIRT2TDP1CCR1CCR5
SCHEMBL20108893 0.90 TRPV1 (0.37) TOP1CYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL20108874 0.89 TOP1 (0.38) TOP1SIRT2CYP17A1CYP19A1CYP11B1
SCHEMBL20108887 0.88 TOP1 (0.37) TOP1MEN1KMT2AKDM4EGMNN
SCHEMBL20108853 0.87 TOP1 (0.38) TOP1TDP1CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX TOP1 2172/4885SIRT2 1420/4885CYP17A1 4057/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX TOP1 2172/4885SIRT2 1420/4885CYP17A1 4057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.