Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108887

SCHEMBL20108887

SCHEMBL20108887

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc3c(-c4ccc5ccccc5n4)c4cc(-c5ccc6ccc7cccnc7c6n5)ccc4c(-c4ccc5ccccc5n4)c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 8/20 0.37
▸ AR P10275 6/20 0.35
▸ MCL1 Q07820 1/20 0.35
▸ NPC1 O15118 4/20 0.35
▸ RAB9A P51151 4/20 0.35
▸ KDM4E B2RXH2 3/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ CYP2C9 P11712 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ MAPT P10636 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ NFKB1 P19838 1/20 0.34
▸ NFKB2 Q00653 1/20 0.34
▸ RELA Q04206 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ MEN1 O00255 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108892 0.91 TOP1 (0.37) TOP1KDM4ESMN1; SMN2CYP2C9CYP3A4
SCHEMBL20108843 0.90 TOP1 (0.38) TOP1KDM4ESMN1; SMN2CYP3A4CYP2D6
SCHEMBL20108835 0.90 TOP1 (0.38) TOP1KDM4ESMN1; SMN2CYP3A4CYP2D6
SCHEMBL20108844 0.88 TOP1 (0.37) TOP1KDM4ESMN1; SMN2CYP2C9CYP3A4
SCHEMBL20108845 0.87 TOP1 (0.37) TOP1KDM4ESMN1; SMN2CYP3A4CYP2D6
SCHEMBL20108874 0.85 TOP1 (0.38) TOP1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL20108873 0.85 TOP1 (0.36) TOP1KDM4ESMN1; SMN2CYP2C9CYP3A4
SCHEMBL20108893 0.84 TRPV1 (0.37) TOP1NPC1KDM4ESMN1; SMN2CYP2C9
SCHEMBL20108848 0.84 CCR1 (0.39) TOP1ARKDM4EALDH1A1SMN1; SMN2
SCHEMBL20108853 0.81 TOP1 (0.38) TOP1KDM4ESMN1; SMN2CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX TOP1 2172/4885AR 3068/4885MCL1 4069/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX TOP1 2172/4885AR 3068/4885MCL1 4069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.