SCHEMBL20108897

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17403775	0.91	PARP1 (0.46)	NPC1RAB9APARP1KDM4EKMT2A
	SCHEMBL17899346	0.85	NOTUM (0.58)	CYP2C9ARNPC1RAB9ACYP1A2
	SCHEMBL17403770	0.85	MMP2 (0.46)	CYP3A4CYP2D6PARP1KDM4EMAPT
	SCHEMBL17174105	0.85	PARP1 (0.46)	RAB9APARP1KDM4EKMT2AMAPT
	SCHEMBL17174126	0.85	PARP1 (0.39)	ARNPC1RAB9ADHODHPARP1
	SCHEMBL17174127	0.85	PARP1 (0.46)	RAB9APARP1KDM4EKMT2AMAPT
	SCHEMBL17174111	0.84	PARP1 (0.41)	RAB9ADHODHPARP1KMT2AMAPT
	SCHEMBL20108846	0.84	CYP1A1 (0.45)	CYP2C9ARNPC1RAB9ACYP1A2
	SCHEMBL20108905	0.83	CYP2C9 (0.39)	CYP2C9ARNPC1RAB9ACYP1A2
	SCHEMBL20108882	0.82	PARP1 (0.40)	RAB9APARP1KMT2ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.