Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108913

SCHEMBL20108913

SCHEMBL20108913

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc3c(-c4ccccc4)c4cc(-c5ccc6ccc7ccc(-c8ccccn8)nc7c6n5)ccc4c(-c4ccccc4)c3c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 1/20 0.35
▸ PRMT5 O14744 2/20 0.34
▸ WDR77 Q9BQA1 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ TP53 P04637 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ SIRT2 Q8IXJ6 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ PLG P00747 1/20 0.33
▸ PLAU P00749 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ KLF5 Q13887 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ CCR1 P32246 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108835 0.90 TOP1 (0.38) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL20108843 0.90 TOP1 (0.38) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL20108862 0.90 TOP1 (0.39) TOP1PRMT5CYP2C9TP53RAB9A
SCHEMBL20108892 0.89 TOP1 (0.37) TOP1PRMT5WDR77CYP2C9KDM4E
SCHEMBL13046226 0.88 KDM4E (0.40) PRMT5WDR77KDM4ELMNATP53
SCHEMBL20108845 0.87 TOP1 (0.37) TOP1KDM4ELMNATP53SMN1; SMN2
SCHEMBL20108893 0.85 TRPV1 (0.37) TOP1CYP2C9KDM4ELMNATP53
SCHEMBL20108844 0.84 TOP1 (0.37) TOP1CYP2C9KDM4ELMNATP53
SCHEMBL20108900 0.83 CYP2C9 (0.39) TOP1CYP2C9KDM4ELMNATP53
SCHEMBL13046182 0.82 KDM4E (0.42) KDM4ELMNATP53SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX TOP1 2172/4885PRMT5 4185/4885WDR77 3902/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX TOP1 2172/4885PRMT5 4185/4885WDR77 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.