SCHEMBL13046226

SCHEMBL13046226

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccccc5)cc4)c4cc(-c5cccc(-c6ccc7ccc8ccc(-c9ccccn9)nc8c7n6)c5)ccc34)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.40
LMNA P02545 4/20 0.40
TP53 P04637 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
CCR1 P32246 3/20 0.40
CCR5 P51681 3/20 0.40
CCR8 P51685 3/20 0.40
ALOX15 P16050 2/20 0.40
MAPK1 P28482 2/20 0.40
HTT P42858 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALPL P05186 1/20 0.40
HSP90AA1 P07900 1/20 0.40
ALPI P09923 1/20 0.40
ALPG P10696 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
RAB9A P51151 3/20 0.36
HSD17B10 Q99714 3/20 0.36
ALDH1A1 P00352 2/20 0.36
PKM P14618 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13046182 0.94 KDM4E (0.42) KDM4ELMNATP53SMN1; SMN2CCR1
SCHEMBL10354071 0.90 SMN1; SMN2 (0.50) KDM4ELMNATP53SMN1; SMN2CCR1
SCHEMBL19768271 0.89 KDM4E (0.45) KDM4ELMNATP53SMN1; SMN2CCR1
SCHEMBL21103665 0.89 PARP1 (0.40) RAB9ADHODHMEN1KMT2ACYP1A2
SCHEMBL10353574 0.88 CCR1 (0.40) KDM4ELMNATP53SMN1; SMN2CCR1
SCHEMBL20108913 0.88 TOP1 (0.35) KDM4ELMNATP53SMN1; SMN2CCR1
SCHEMBL10353225 0.87 LMNA (0.50) KDM4ELMNATP53SMN1; SMN2CCR1
SCHEMBL13046243 0.87 LMNA (0.37) KDM4ELMNATP53SMN1; SMN2CCR1
SCHEMBL21103931 0.87 PARP1 (0.41) KDM4ELMNARAB9AALDH1A1HPGD
SCHEMBL10300960 0.87 SMN1; SMN2 (0.53) KDM4ELMNATP53SMN1; SMN2CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552259-B1 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20220393113-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-08 US disclosed
US-10573823-B2 Organic electroluminescent device JOLED INC (JP) 2020-02-25 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150069351-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-03-12 US disclosed
EP-2833700-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed
US-7834346-B2 Nitrogenous heterocyclic derivative and organic electroluminescence device making use of the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-16 US disclosed
US-7834346-B2 Nitrogenous heterocyclic derivative and organic electroluminescence device making use of the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-16 US disclosed
US-20100108990-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-05-06 US disclosed
US-20100108990-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108990-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME CYBA, NUDC, NUDT1 KDM4E 636/4885LMNA 936/4885TP53 4486/4885
US-10573823-B2 Organic electroluminescent device L1CAM, NES, EML4 KDM4E 2954/4885LMNA 831/4885TP53 4070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.