Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109242 | 0.83 | HSD17B10 (0.42) | HSD17B10CYP3A4TSHRLMNAHPGD | |
| SCHEMBL20109206 | 0.83 | HSD17B10 (0.42) | HSD17B10CYP3A4TSHRLMNAHPGD | |
| SCHEMBL17596724 | 0.76 | KMT2A (0.34) | TSHRLMNANPC1RAB9AMEN1 | |
| SCHEMBL20109318 | 0.75 | CES2 (0.37) | TSHRLMNAHPGDNPC1RAB9A | |
| SCHEMBL20109157 | 0.72 | HSD17B10 (0.41) | HSD17B10CYP3A4TSHRHPGDNPC1 | |
| SCHEMBL20109181 | 0.72 | HSD17B10 (0.41) | HSD17B10CYP3A4TSHRHPGDNPC1 | |
| SCHEMBL17595853 | 0.72 | MMP8 (0.43) | CYP3A4LMNAHPGDMEN1KMT2A | |
| SCHEMBL17596740 | 0.69 | MAPT (0.34) | HSD17B10CYP3A4TSHRLMNANPC1 | |
| SCHEMBL17596817 | 0.69 | MMP8 (0.50) | TSHRTDP1POLBGFER | |
| SCHEMBL17596737 | 0.68 | PHGDH (0.35) | LMNANPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | HSD17B10 4053/4885CYP3A4 2080/4885TSHR 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.