Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109225 | 0.87 | ALDH1A1 (0.41) | ALDH1A1TSHRGLAGAAMAPT | |
| SCHEMBL20109256 | 0.87 | ALDH1A1 (0.41) | ALDH1A1TSHRGLAGAAMAPT | |
| SCHEMBL17595869 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRGAAHPGDMAPT | |
| SCHEMBL17596436 | 0.84 | GAA (0.39) | ALDH1A1TSHRGAAHPGDMAPT | |
| SCHEMBL20109280 | 0.81 | GAA (0.39) | ALDH1A1TSHRGAAMAPTNPC1 | |
| SCHEMBL20109272 | 0.81 | GAA (0.40) | ALDH1A1TSHRGAAMAPTNPC1 | |
| SCHEMBL17596725 | 0.80 | GAA (0.40) | ALDH1A1GAAHPGDMAPTL3MBTL1 | |
| SCHEMBL17596810 | 0.80 | MMP8 (0.48) | ALDH1A1TSHRGAAHPGDMAPT | |
| SCHEMBL20109319 | 0.79 | NOTUM (0.43) | ALDH1A1GAAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL20109328 | 0.78 | NPC1 (0.37) | ALDH1A1TSHRGAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | ALDH1A1 4621/4885TSHR 4125/4885GLA 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.