Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109134 | 0.86 | DHODH (0.33) | CYP2D6KDM4EALDH1A1GFERL3MBTL1 | |
| SCHEMBL20109250 | 0.82 | CYP2D6 (0.36) | CYP2D6ELOVL1KCNQ2KDM4EALDH1A1 | |
| SCHEMBL20109219 | 0.82 | ATM (0.37) | CYP2D6ELOVL1KCNQ2KDM4EALDH1A1 | |
| SCHEMBL20109131 | 0.77 | CYP2C19 (0.35) | KDM4EALDH1A1SMN1; SMN2LMNACYP2C19 | |
| SCHEMBL17596724 | 0.77 | KMT2A (0.34) | KCNQ2KDM4EALDH1A1TP53KMT2A | |
| SCHEMBL17596436 | 0.75 | GAA (0.39) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL20109140 | 0.73 | CHRNA7 (0.36) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL20109145 | 0.72 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20109272 | 0.72 | GAA (0.40) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL20109215 | 0.70 | ATM (0.33) | CYP2D6KDM4EALDH1A1GFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | CYP2D6 3429/4885ELOVL1 3869/4885KCNQ2 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.