Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109189 | 0.73 | — | — | |
| SCHEMBL20109169 | 0.72 | KDM4E (0.32) | KDM4ESMN1; SMN2 | |
| SCHEMBL19383783 | 0.66 | — | — | |
| SCHEMBL20109144 | 0.63 | NPSR1 (0.32) | KDM4E | |
| SCHEMBL9588855 | 0.61 | — | — | |
| SCHEMBL11242744 | 0.61 | — | — | |
| SCHEMBL23421922 | 0.61 | ALDH1A1 (0.39) | KDM4ESMN1; SMN2 | |
| SCHEMBL16560332 | 0.58 | TSHR (0.46) | KDM4ESMN1; SMN2 | |
| SCHEMBL5660160 | 0.57 | — | — | |
| SCHEMBL10845200 | 0.57 | FAAH (0.41) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | KDM4E 3603/4885SMN1; SMN2 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.