Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109216 | 0.86 | MAPT (0.37) | CHRNA7MAPK1MAPTDRD2SIGMAR1 | |
| SCHEMBL20109241 | 0.83 | CHRNA7 (0.32) | CHRNA7MAPTDRD2SIGMAR1 | |
| SCHEMBL20109209 | 0.82 | CHRNA7 (0.33) | CHRNA7MAPTDRD2SIGMAR1 | |
| SCHEMBL20109210 | 0.82 | CHRNA7 (0.33) | CHRNA7MAPTDRD2SIGMAR1 | |
| SCHEMBL20113896 | 0.81 | HPGD (0.36) | NPC1L3MBTL1MAPT | |
| SCHEMBL20109208 | 0.81 | SMN1; SMN2 (0.40) | CHRNA7NPC1MAPK1MAPT | |
| SCHEMBL20109212 | 0.80 | TRPA1 (0.32) | CHRNA7L3MBTL1MAPTDRD2SIGMAR1 | |
| SCHEMBL20109214 | 0.74 | CHRNA7 (0.36) | CHRNA7MAPK1MAPTDRD2SIGMAR1 | |
| SCHEMBL17596734 | 0.72 | RBP4 (0.38) | MAPK1MAPTDRD2 | |
| SCHEMBL21866419 | 0.72 | RBP4 (0.38) | MAPK1MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | CHRNA7 3780/4885NPC1 1228/4885MAPK1 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.