Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109237 | 0.86 | MAPT (0.37) | CHRNA7ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL20109212 | 0.83 | TRPA1 (0.32) | TRPA1CHRNA7KDM4EALDH1A1GFER | |
| SCHEMBL20109135 | 0.83 | TRPA1 (0.32) | TRPA1CHRNA7KDM4EALDH1A1GFER | |
| SCHEMBL20109233 | 0.82 | CHRNA7 (0.33) | CHRNA7MAPTDRD2SIGMAR1 | |
| SCHEMBL20109236 | 0.82 | CHRNA7 (0.33) | CHRNA7MAPTDRD2SIGMAR1 | |
| SCHEMBL20113546 | 0.81 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL20109235 | 0.81 | SMN1; SMN2 (0.40) | CHRNA7KDM4EALDH1A1MAPT | |
| SCHEMBL20109241 | 0.80 | CHRNA7 (0.32) | CHRNA7MAPTDRD2SIGMAR1 | |
| SCHEMBL20109216 | 0.74 | MAPT (0.37) | CHRNA7ALDH1A1MAPTDRD2SIGMAR1 | |
| SCHEMBL20109240 | 0.74 | CHRNA7 (0.36) | CHRNA7ADRA2AADRA2BADRA2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | TRPA1 2417/4885CHRNA7 3780/4885ADRA2A 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.