Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523040 | 0.91 | KCNH2 (0.55) | KCNH2MEN1KMT2ALMNATAAR1 | |
| SCHEMBL20110029 | 0.84 | KCNH2 (0.44) | KCNH2LMNATAAR1ALDH1A1ALOX15 | |
| SCHEMBL16015472 | 0.84 | KCNH2 (0.53) | KCNH2MEN1KMT2ALMNATAAR1 | |
| SCHEMBL20109296 | 0.79 | KCNH2 (0.68) | KCNH2NOS1NOS2NPSR1 | |
| SCHEMBL3630858 | 0.76 | GRIN2D (0.44) | KCNH2LMNANOS1NOS2NPSR1 | |
| SCHEMBL20109293 | 0.75 | KCNH2 (0.55) | KCNH2ALDH1A1NOS1NOS3NOS2 | |
| SCHEMBL20298968 | 0.75 | KCNH2 (0.46) | KCNH2MEN1KMT2ALMNATAAR1 | |
| SCHEMBL20109822 | 0.75 | LMNA (0.40) | MEN1KMT2ALMNATAAR1ALDH1A1 | |
| SCHEMBL20108965 | 0.71 | MTNR1A (0.47) | KCNH2NPSR1 | |
| SCHEMBL4067485 | 0.70 | HRH3 (0.79) | MEN1KMT2ALMNATAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534152-B1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-02 | — | — | EP | disclosed |